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![]() ![]() For distal radius fractures, both osteopenia and osteoporosis had a higher risk (HR 4.31 95%CI 2.59–7.15 and 4.81 95%CI 2.70–8.58). In adjusted models, those with osteoporosis had a higher likelihood of any fracture (HR 2.12 95%CI 1.50–2.98). For distal radius fracture, the AUROC for BMD UDforearm was higher than other sites and FRAX ( p < 0.05). AUROCs for continuous BMD UDforearm, 33% forearm(BMD 33%forearm), BMD hip, BMD spine, and FRAX without BMD were similar for any fracture ( p > 0.05). In adjusted models, continuous BMD UDforearm was associated with any (HR 1.26 95%CI 1.15–1.39) and distal radius fractures (HR 1.59 95%CI 1.38–1.83). ![]() ![]() Resultsĭuring 14,270 person-years of follow-up, there were 318 fractures (85 distal radius). Analyses were conducted for any fracture and distal radius fractures. Areas under receiver operating characteristics (AUROC) curves were calculated. Using Cox proportional hazard models, hazard ratios (HR) were calculated for BMD UDforearm as a continuous variable (expressed as a one-unit decrease in T-score) and a categorical variable (normal/osteopenia/osteoporosis). Incident low-trauma fractures were radiologically verified. Using a Lunar DPX-L, Geelong Osteoporosis Study women ( n = 1026), aged 40–90 years, had BMD measured. More data are needed to understand how ultra-distal forearm BMD (BMD UDforearm) may assist fracture prediction. Purposeįemoral neck (BMD hip) and lumbar spine (BMD spine) bone mineral density (BMD) are routinely used to assess fracture risk. Bone mineral density measured at the ultra-distal forearm site was associated with any fracture, as well as distal radius fracture in women from a longitudinal cohort study. ![]()
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